Chromatin alterations in response to forced swimming underlie increased prodynorphin transcription
نویسندگان
چکیده
منابع مشابه
Chromatin alterations in response to forced swimming underlie increased prodynorphin transcription.
Antagonism of the kappa opioid receptor (KOR) has been reported to have anti-depressant-like properties. The dynorphin/KOR system is a crucial neurochemical substrate underlying the pathologies of addictive diseases, affective disorders and other disease states. However, the molecular underpinnings and neuroanatomical localization of the dysregulation of this system have not yet been fully eluc...
متن کاملOvarian and uterine alterations following forced swimming: An immunohistochemical study
BACKGROUND Physical exercise is known to be a stressor stimulus that leads to reproductive disruption. OBJECTIVE The aim of this study was to evaluate the effect of forced swimming on the uterus and ovaries in mice. MATERIALS AND METHODS Adult mice (N=24) were divided into the following three groups: A, control; B, swimming in water (10oC); and C, swimming in water (23oC). Swimmers swam for...
متن کاملovarian and uterine alterations following forced swimming: an immunohistochemical study
background: physical exercise is known to be a stressor stimulus that leads to reproductive disruption.objective: the aim of this study was to evaluate the effect of forced swimming on the uterus and ovaries in mice.materials and methods: adult mice (n=24) were divided into the following threegroups: a, control; b, swimming in water (10popc); and c, swimming in water (23popc).swimmers swam for ...
متن کاملDedifferentiation of tobacco cells is associated with ribosomal RNA gene hypomethylation, increased transcription, and chromatin alterations.
Epigenetic changes accompanying plant cell dedifferentiation and differentiation are reported in 35S ribosomal DNA (rDNA) of tobacco (Nicotiana tabacum). There was a reduction of CG and CNG methylation in both intergenic and genic regions of the rDNA cistron in fully dedifferentiated callus and root compared to leaf. The rDNA hypomethylation was not random, but targeted to particular rDNA gene ...
متن کاملP-104: In Vivo Study of Follicogenesis and Estradiol Level in Mouse Exposed To Forced Swimming
Background: Strenuous exercise and temperature outside the optimum are associated with hypothalamic dysfunction and therefore disruption of fertility in females. The aim of this study was to evaluate serum Estradiol level and follicogenesis in adult mice exposed to forced swimming in different temperature waters. Materials and Methods: Adult female mice were randomly divided into four groups as...
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ژورنال
عنوان ژورنال: Neuroscience
سال: 2012
ISSN: 0306-4522
DOI: 10.1016/j.neuroscience.2012.06.006